Why INT2ACT?
Being part of INT2ACT means working with inspiring researchers from academia and industry. Together, we are exploring new ways to use nucleic acid technologies to improve personalized medicine. I am really excited about this opportunity.
Dr. Jeny Shklover is a Lab Manager and Senior Scientist within the Wolfson Faculty of Chemical Engineering at Technion – Israel Institute of Technology in Haifa, Israel.
Dr. Jeny Shklover joined the laboratory lead by Prof. Avi Schroeder in 2019. Research in the laboratory focuses on the development of innovative medical nano-technologies for targeted drug delivery and personalized medicine, with applications in cancer and neurodegenerative diseases, as well as the design of synthetic cells for therapeutic use and food-related applications. Dr. Shklover is part of the laboratory’s scientific and strategic leadership, overseeing projects execution, and regulatory compliance. In addition, she directs the laboratory’s collaborations with industry partners and coordinates European research initiatives.
From a young age, I was drawn to quests, and science became the most meaningful one. This curiosity led me to the field of targeted drug delivery and nanotechnology, where we work to develop innovative therapeutic solutions that bridge fundamental research and patient care.
After completing a Master’s degree, where I explored the role of quadruplex DNA structures in regulating gene expression, I obtained my Ph.D. from the Technion – Israel Institute of Technology in 2015. My doctoral research focused on the molecular and cellular basis of Drosophila embryonic cell clearance in the central nervous system and was supported by the Clore Foundation Scholarship. Following my Ph.D., I pursued postdoctoral research at UC Davis, USA, focusing on endothelial cell recellularization of xenogeneic scaffolds and the development of novel antigen removal methods. Since 2019, I have been a lab manager and senior scientists of Prof. Avi Schroeder’s research group at Technion, exploring drug delivery and theranostics approaches for cancer and neurodegenerative diseases, while also overseeing industry collaborations, European research partnerships, and grant proposal management.
Mora-Raimundo, P., Gilon, A., Kadosh, H., Richtman, Y., Sela, M., Ackerman, S., Chen, G., Abel, R., Kagan, S., Sharf-Pauker, N., Gigi, O., Abumanhal-Masarweh, H., Tripathi, U., Saada, M., Shemen, A., Link-Sourani, D., Shklover, J., Farah, R., Horowitz-Kraus, T., Hadjidemetriou, M., Kostarelos, K., Stern, S., Schroeder, A. (2025) Music enhances lipid nanoparticle brain delivery and mRNA transfection in brain cells. Journal of Controlled Release 114301. https://doi.org/10.1016/j.jconrel.2025.114301
Sela, M., Chen, G., Kadosh, H., Kagan, T., Nicola, R., Turutov, S., Richtman, Y., Zhige, L., Albalak Menasherov, M. R., Kagan, S., Schroeder, T., Mora-Raimundo, P., Kablan, R., Egorov, E., Odeh, A., Abu-Raiya, T., Ionita, I., Freilich, I., Kaneti, G., Knani, I., Arav, Y., Leichtmann-Bardoogo, Y., Tadmor, K., Shklover, J., Patriarchi, T., Danino, D., Hasson, P., Ashery, U., Zeisel, A., Maoz, B. M., Laviv, T., Radinsky, K., Schroeder, A. (2025) AI-Validated Brain Targeted mRNA Lipid Nanoparticles with Neuronal Tropism. ACS Nano. https://doi.org/10.1021/acsnano.4c15013
Sela, M., Poley, M., Mora-Raimundo, P., Kagan, S., Avital, A., Kaduri, M., Chen, G., Adir, O., Rozencweig, A., Weiss, Y., Sade, O., Leichtmann-Bardoogo, Y., Simchi, L., Aga-Mizrachi, S., Bell, B., Yeretz-Peretz, Y., Zaid Or, A., Choudhary, A., Rosh, I., Cordeiro, D., Cohen-Adiv, S., Berdichevsky, Y., Odeh, A., Shklover, J., Shainsky-Roitman, J., Schroeder, J. E., Hershkovitz, D., Hasson, P., Ashkenazi, A., Stern, S., Laviv, T., Ben-Zvi, A., Avital, A., Ashery, U., Maoz, B. M., Schroeder, A. (2023) Brain-targeted liposomes loaded with monoclonal antibodies reduce alpha-synuclein aggregation and improve behavioral symptoms in Parkinson’s disease. Advanced Materials 35(51), 2304654. https://doi.org/10.1002/adma.202304654
Kaduri, M., Sela, M., Kagan, S., Poley, M., Abumanhal-Masarweh, H., Mora-Raimundo, P., Ouro, A., Dahan, N., Hershkovitz, D., Shklover, J., Shainsky-Roitman, J., Buganim, Y., Schroeder, A. (2021) Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases. Science Advances 7, eabj5435. https://doi.org/10.1126/sciadv.abj5435
Artzy-Schnirman, A., Arber Raviv, S., Doppelt Flikshtain, O., Shklover, J., Korin, N., Gross, A., Mizrahi, B., Schroeder, A., Sznitman, J. (2021) Advanced human-relevant in vitro pulmonary platforms for respiratory therapeutics. Advanced Drug Delivery Reviews 176, 113901. https://doi.org/10.1016/j.addr.2021.113901